Search Contact information
University of Cambridge Home Department of Engineering
University of Cambridge > Engineering Department > Machine Intelligence Lab

Abstract for treece_tr665

Cambridge University Engineering Department Technical Report CUED/F-INFENG/TR665

IMAGING THE FEMORAL CORTEX: THICKNESS, DENSITY AND MASS FROM CLINICAL CT

G.M. Treece, K.E.S. Poole and A.H. Gee

29 April 2011

There is growing evidence that focal thinning of cortical bone in the proximal femur may predispose a hip to fracture. Detecting such defects in clinical CT is challenging, since cortices may be significantly thinner than the imaging system's point spread function. We recently proposed a model-fitting technique to measure sub-millimetre cortices, an ill-posed problem which was regularized by assuming a specific, fixed value for the cortical density. In this paper, we develop the work further by proposing and evaluating a more rigorous method for estimating the constant cortical density, and extend the paradigm to encompass the mapping of cortical mass (mineral mg/cm2) in addition to thickness. Density, thickness and mass estimates are evaluated on sixteen cadaveric femurs, with high resolution measurements from a micro-CT scanner providing the gold standard. The results demonstrate robust, accurate measurement of peak cortical density and cortical mass. Cortical thickness errors are confined to regions of thin cortex and are bounded by the extent to which the local density deviates from the peak, averaging 20% for 0.5 mm cortex.

[3.6 MBytes PDF, 20 pages]


(ftp:) treece_tr665.pdf (http:) treece_tr665.pdf

If you have difficulty viewing files that end '.gz', which are gzip compressed, then you may be able to find tools to uncompress them at the gzip web site.

If you have difficulty viewing files that are in PostScript, (ending '.ps' or '.ps.gz'), then you may be able to find tools to view them at the gsview web site.

We have attempted to provide automatically generated PDF copies of documents for which only PostScript versions have previously been available. These are clearly marked in the database - due to the nature of the automatic conversion process, they are likely to be badly aliased when viewed at default resolution on screen by acroread.

© 2005 Cambridge University Engineering Dept
Information provided by milab-maintainer